ARK2C - arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C Gene

Also Known as ARKL2; RNF165; lncAMPC; RNF111L2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 494470

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in motor neuron axon guidance and positive regulation of BMP signaling pathway. Predicted to act upstream of or within several processes, including forelimb morphogenesis; nervous system development; and protein polyubiquitination. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Biased expression in brain (RPKM 3.7), spleen (RPKM 1.6) and 12 other tissues.

ARK2C Products (2)

mRNA Protein Name
NM_001256758.1 NP_001243687.1 E3 ubiquitin-protein ligase ARK2C isoform 2
NM_152470.3 NP_689683.2 E3 ubiquitin-protein ligase ARK2C isoform 1

ARK2C Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ARK2C Q6ZSG1 SKI Homo sapiens P12755
Anti Tag CoIP
23610558
Cross: Cross-species interaction Intra: Intraspecies interaction