2. Gene
  3. Tnfrsf11a - TNF receptor superfamily member 11A Gene

Tnfrsf11a - TNF receptor superfamily member 11A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RANK; RGD1563614

Gene ID: 498206 | Gene type: protein coding

About Tnfrsf11a

Primary_assembly 13: 21,928,408-21,986,695 forward strand.mRatBN7.2:CM026986.1

This gene has 1 transcript (splice variant), 493 orthologues, 20 paralogues and is associated with 16 phenotypes. Biased expression in Lung (RPKM 26.6), Brain (RPKM 24.) and 9 other tissues.

Summary

Predicted to enable cytokine binding activity and tumor necrosis factor-activated receptor activity. Involved in response to radiation. Predicted to be located in cell surface; cytosol; and plasma membrane. Predicted to be active in external side of plasma membrane. Biomarker of myocarditis. Human ortholog(s) of this gene implicated in Paget's disease of bone; autosomal recessive osteopetrosis 7; bone development disease; familial expansile osteolysis; and osteoporosis. Orthologous to human TNFRSF11A (TNF Receptor Superfamily member 11a). [provided by Alliance of Genome Resources, Apr 2022]

Tnfrsf11a Products(1)

mRNA Protein Name
NM_001271235.1 NP_001258164.1 tumor necrosis factor receptor superfamily member 11A precursor

Tnfrsf11a Protein Structure

TNFRSF11A

TNFRSF11A: cd13411 (33 - 195)

TNFRSF11A

TNFRSF11A: cd13411 (34 - 68)

TNFRSF11A

TNFRSF11A: cd13411 (71 - 112)

TNFRSF11A

TNFRSF11A: cd13411 (114 - 151)

TNFRSF11A

TNFRSF11A: cd13411 (154 - 194)

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  • 633 a.a.
Protein Preferred Names Protein Names

tumor necrosis factor receptor superfamily member 11A

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Recombinant Tnfrsf11a Proteins

Cat. No. Product Name Accession Purity
HY-P76562 RANK/TNFRSF11A Protein, Rat (HEK293, Fc) F1M8Z6 (M1-P213) ≥95%
HY-P76563 RANK/TNFRSF11A Protein, Rat (HEK293, His) F1M8Z6 (M1-P213) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14799 TNFRSF11A Human Pre-designed siRNA Set A / Unkown
HY-RS14800 Tnfrsf11a Mouse Pre-designed siRNA Set A / Unkown
HY-RS14801 Tnfrsf11a Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfrsf11a NCBI NCBI:8792
Mus musculus Tnfrsf11a NCBI NCBI:21934