Tnfrsf11a - TNF receptor superfamily member 11A Gene

Also Known as RANK; RGD1563614

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 498206

About Tnfrsf11a

Primary_assembly 13: 21,928,408-21,986,695 forward strand.mRatBN7.2:CM026986.1

This gene has 1 transcript (splice variant), 493 orthologues, 20 paralogues and is associated with 16 phenotypes. Biased expression in Lung (RPKM 26.6), Brain (RPKM 24.) and 9 other tissues.

Summary

Predicted to enable cytokine binding activity and tumor necrosis factor-activated receptor activity. Involved in response to radiation. Predicted to be located in cell surface; cytosol; and plasma membrane. Predicted to be active in external side of plasma membrane. Biomarker of myocarditis. Human ortholog(s) of this gene implicated in Paget's disease of bone; autosomal recessive osteopetrosis 7; bone development disease; familial expansile osteolysis; and osteoporosis. Orthologous to human TNFRSF11A (TNF Receptor Superfamily member 11a). [provided by Alliance of Genome Resources, Apr 2022]

Tnfrsf11a Products (1)

mRNA Protein Name
NM_001271235.1 NP_001258164.1 tumor necrosis factor receptor superfamily member 11A precursor

Tnfrsf11a Protein Structure

TNFRSF11A

TNFRSF11A: cd13411 (33 - 195)

TNFRSF11A

TNFRSF11A: cd13411 (34 - 68)

TNFRSF11A

TNFRSF11A: cd13411 (71 - 112)

TNFRSF11A

TNFRSF11A: cd13411 (114 - 151)

TNFRSF11A

TNFRSF11A: cd13411 (154 - 194)

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  • 633 a.a.
Protein Preferred Names Protein Names

tumor necrosis factor receptor superfamily member 11A

  • tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Recombinant Tnfrsf11a Proteins

Cat. No. Product Name Accession Purity
HY-P76562 RANK/TNFRSF11A Protein, Rat (HEK293, Fc) NP_001258164.1 (V31-P213) ≥ 80%, as determined by reducing SDS-PAGE.
HY-P76563 RANK/TNFRSF11A Protein, Rat (HEK293, His) XP_573424.2 (V31-P213) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14800 Tnfrsf11a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14801 Tnfrsf11a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14799 TNFRSF11A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfrsf11a NCBI NCBI:8792