ACOX1 - Acox1 acyl-CoA oxidase 1 Gene

Also Known as ACO; AOX; aCoA; RATACOA1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 50681

Summary

Enables anion binding activity; palmitoyl-CoA oxidase activity; and protein homodimerization activity. Involved in fatty acid beta-oxidation using acyl-CoA oxidase. Located in peroxisome. Human ortholog(s) of this gene implicated in peroxisomal acyl-CoA oxidase deficiency. Orthologous to human ACOX1 (acyl-CoA oxidase 1). [provided by Alliance of Genome Resources, Apr 2022]

ACOX1 Products (2)

mRNA Protein Name
NM_001414015.1 NP_001400944.1 peroxisomal acyl-coenzyme A oxidase 1 isoform 1
NM_017340.3 NP_059036.1 peroxisomal acyl-coenzyme A oxidase 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acyl-CoA oxidase activity IDA
IDA: Inferred from direct assay
7462191 RGD
enables fatty acid binding IDA
IDA: Inferred from direct assay
1400324 RGD
enables flavin adenine dinucleotide binding IDA
IDA: Inferred from direct assay
11872165 RGD
enables palmitoyl-CoA oxidase activity IDA
IDA: Inferred from direct assay
1400324 RGD
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
11872165 RGD
Biological Process GO Annotation Evidence References Source
involved in fatty acid beta-oxidation using acyl-CoA oxidase IDA
IDA: Inferred from direct assay
1400324 RGD
Cellular Component GO Annotation Evidence References Source
located in peroxisome IDA
IDA: Inferred from direct assay
1400324 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peroxisomal acyl-coenzyme A oxidase 1

  • acyl-CoA oxidase 1, palmitoyl

  • acyl-Coenzyme A oxidase 1, palmitoyl

  • palmitoyl-CoA oxidase

  • peroxisomal acyl-coenzyme A oxidase 1-like

  • peroxisomal fatty acyl-CoA oxidase

  • straight-chain acyl-CoA oxidase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-135425 10,12-Tricosadiynoic acid Inhibitor 99.95% Unkown
HY-N1966 (E)-Osmundacetone 99.81% Unkown
HY-N0853A Alisol A 24-acetate 98.0% Unkown
HY-RS00182 ACOX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17057 Acox1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23501 Acox1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ACOX1 NCBI NCBI:51