Klf13 - Kruppel-like factor 13 Gene

Also Known as Bteb3; FKLF2; NSLP1; FKLF-2; RFLAT1; RFLAT-1; 0610043C13Rik; 9430029L20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50794

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of cell population proliferation and negative regulation of erythrocyte differentiation. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and neural retina. Orthologous to human KLF13 (Kruppel like factor 13). [provided by Alliance of Genome Resources, Apr 2022]

Klf13 Products (1)

mRNA Protein Name
NM_021366.3 NP_067341.2 Krueppel-like factor 13
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
10642511 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
10642511 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10642511 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
28164238 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
18285334 MGI
involved in negative regulation of erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
18285334 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
10642511 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
10642511 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Krueppel-like factor 13

  • BTE-binding protein 3

  • C2-H2 zinc finger protein

  • RANTES factor of late activated T-lymphocytes 1

  • basic transcription element-binding protein 3

  • erythroid transcription factor FKLF-2

  • transcription factor BTEB3

Klf13 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Klf13 Q9JJZ6 Tbx5 Mus musculus P70326 28164238
Cross: Cross-species interaction Intra: Intraspecies interaction

Orthologs Information

Species Symbol Source ID
Homo sapiens Klf13 NCBI NCBI:51621