Nasp - nuclear autoantigenic sperm protein (histone-binding) Gene
Also Known as Epcs32; Nasp-T; D4Ertd767e; 5033430J04Rik
Species: Mus musculus
Gene Type: protein coding
Gene ID: 50927
Summary
Enables histone binding activity. Involved in G1/S transition of mitotic cell cycle; blastocyst development; and histone exchange. Acts upstream of or within DNA replication-dependent chromatin assembly. Located in cytoplasm and nucleus. Is expressed in several structures, including brain ventricular layer; extraembryonic component; lung; metanephros; and rest of cerebellum marginal layer. Orthologous to human NASP (nuclear autoantigenic sperm protein). [provided by Alliance of Genome Resources, Apr 2022]
Nasp Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001081475.1 | NP_001074944.1 | nuclear autoantigenic sperm protein isoform 1 |
| NM_001284229.1 | NP_001271158.1 | nuclear autoantigenic sperm protein isoform 3 |
| NM_016777.3 | NP_058057.3 | nuclear autoantigenic sperm protein isoform 2 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables histone binding |
IDA
IDA: Inferred from direct assay
|
10893414 | MGI |
| enables histone chaperone activity |
IDA
IDA: Inferred from direct assay
|
12509435 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
10893414 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within DNA replication-dependent chromatin assembly |
IDA
IDA: Inferred from direct assay
|
16728391 | MGI |
| involved in DNA replication-dependent chromatin assembly |
IDA
IDA: Inferred from direct assay
|
12509435 | MGI |
| involved in G1/S transition of mitotic cell cycle |
IDA
IDA: Inferred from direct assay
|
16728391 | MGI |
| involved in blastocyst development |
IMP
IMP: Inferred from mutant phenotype
|
16728391 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
12509435 | MGI |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
10893414 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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| Protein Preferred Names | Protein Names | |
|---|---|---|
|
nuclear autoantigenic sperm protein |
|
