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50999

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8

Inhibitors & Agonists

1

Recombinant Proteins

4

Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15475
    UK-5099
    50+ Cited Publications

    PF-1005023

    		 Mitochondrial Metabolism Cancer
    UK-5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier (MPC). UK-5099 (PF-1005023) inhibits pyruvate-dependent O2 consumption with an IC50 of 50 nM.
    UK-5099
  • HY-41671
    4-Fluorobenzene-1,3-dicarboxylic acid

    NSC 50699; 4-Fluor-isophtalsaeure

    		 Drug Intermediate Others
    4-Fluorobenzene-1,3-dicarboxylic acid (NSC 50699) is a drug intermediate for synthesis of various active compounds.
    4-Fluorobenzene-1,3-dicarboxylic acid
  • HY-12888
    AZD5099

    		Topoisomerase Bacterial Infection
    AZD5099, an antibacterial agent, is a potent and selective bacterial topoisomerase II inhibitor. AZD5099 potently inhibits the infections caused by Gram-positive and fastidious Gram-negative bacteria .
    AZD5099
  • HY-R03245
    mmu-miR-5099 mimic

    		MicroRNA Cancer
    mmu-miR-5099 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-5099 mimic
    mmu-miR-5099 mimic
  • HY-123222
    CGP 56999

    		GABA Receptor Neurological Disease
    CGP 56999 is a potent antagonist GABA(B) receptor, with the IC50 of 0.002 μM. CGP 56999 increased the levels of BDNF mRNA in the brain in vivo and in vitro .
    CGP 56999
  • HY-RI03245A
    mmu-miR-5099 antagomir

    		MicroRNA Cancer
    mmu-miR-5099 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-5099 antagomir
    mmu-miR-5099 antagomir
  • HY-R03245A
    mmu-miR-5099 agomir

    		MicroRNA Cancer
    mmu-miR-5099 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-5099 agomir
    mmu-miR-5099 agomir
  • HY-RI03245
    mmu-miR-5099 inhibitor

    		MicroRNA Cancer
    mmu-miR-5099 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-5099 inhibitor
    mmu-miR-5099 inhibitor

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