GPR173 - G protein-coupled receptor 173 Gene

Also Known as SREB3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54328

About GPR173

Cytogenetic location: Xp11.22 Genomic coordinates (GRCh38): X:53,048,789-53,080,615 (from NCBI)

This gene has 2 transcripts (splice variants), 234 orthologues and 2 paralogues. Broad expression in brain (RPKM 6.2), ovary (RPKM 2.6) and 14 other tissues.

Summary

This gene encodes a member of the G-protein coupled receptor 1 family. This protein contains 7 transmembrane domains and conserved cysteine residues. [provided by RefSeq, Nov 2009]

GPR173 Products (1)

mRNA Protein Name
NM_018969.6 NP_061842.1 probable G-protein coupled receptor 173

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPR173 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (39 - 339)

  • 0
  • 100
  • 200
  • 300
  • 373 a.a.
Protein Preferred Names Protein Names

probable G-protein coupled receptor 173

  • super conserved receptor expressed in brain 3

GPR173 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GPR173 Q9NS66 CBX6 Homo sapiens O95503
Anti Tag CoIP
33961781
Intra
GPR173 Q9NS66 CBX6 Homo sapiens O95503
Anti Tag CoIP
28514442
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Non-Syndromic X-Linked Intellectual Disability 9

  • Mrx44

  • Mrx9

  • X-Linked Mental Retardation 44
Parkinsonism With Spasticity, X-Linked

  • X-Linked Parkinsonism-Spasticity Syndrome

  • XPDS

  • X-Linked Parkinsonism With Spasticity
Non-Syndromic X-Linked Intellectual Disability

  • X-Linked Non-Syndromic Intellectual Disability

  • Non-Specific X-Linked Mental Retardation

  • X-Linked Non-Specific Intellectual Disability
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P5762A Phoenixin-14 TFA / Unkown
HY-RS05683 GPR173 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20162 Gpr173 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26666 Gpr173 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus GPR173 VGNC VGNC:29570
Felis catus GPR173 VGNC VGNC:62687
Rattus norvegicus GPR173 RGD RGD:620748
Macaca mulatta GPR173 VGNC VGNC:72964
Canis familiaris GPR173 VGNC VGNC:41416
Mus musculus GPR173 MGD MGI:1918021
Others GPR173 NCBI