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By Targets:	Apoptosis (1) Bcl-2 Family (1) c-Myc (1) CDK (2) Interleukin Related (1) Neuropeptide Y Receptor (1) SARS-CoV (1)
By Research Areas:	Cancer (1) Infection (1) Inflammation/Immunology (1) Neurological Disease (1)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-143584

AZ5576	CDK Apoptosis	Cancer
AZ5576 is a potent and highly selective CDK9 inhibitor (IC₅₀: <5 nM). AZ5576 inhibits the phosphorylation of RNA polymerase II at Ser2, thereby inhibiting transcriptional elongation. AZ5576 can be used for hematological Malignancy research .

HY-P9949

Reslizumab Sch 55700; CDP-835; JES1-39D10	Interleukin Related	Inflammation/Immunology
Reslizumab (Sch 55700) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab is effective in neutralizing the function of IL-5. Reslizumab has high binding affinity for human IL-5, with K_D values of 109 pM and 4.3 pM in the the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively .

HY-P3692

*CART (55-76), rat*	Neuropeptide Y Receptor	Neurological Disease
CART (55-76), rat is a neuropeptide (55-76 residues of the CART peptide) and constitutes the N-terminal fragments of CART (55-102). CART (55-76), rat is a rat satiety factor with potent appetite-suppressing activity and is closely associated with leptin and neuropeptide Y. CART (55-76), rat can induce anxiety and stress-related behavior .

HY-44484

MAC-5576	SARS-CoV	Infection
MAC-5576 is a SARS-CoV-2 3CL protease inhibitor, with an IC₅₀ of 81 nM. MAC-5576 also inhibits 3CLpro (IC₅₀=0.5 μM), HAV 3Cpro (IC₅₀=0.5 μM), and thrombin (IC₅₀=13 μM) .

HY-111537

rel-AZ5576	c-Myc CDK Bcl-2 Family	Others
rel-AZ5576 is a selective CDK9 inhibitor with the activity of downregulating Mcl-1 and MYC mRNA transcription and protein expression in diffuse large B-cell lymphoma by inhibiting CDK9, promoting MYC protein turnover, reducing MYC phosphorylation on the stable Ser62 residue and downregulating MYC transcriptional targets, inhibiting the growth of diffuse large B-cell lymphoma cell lines in vitro and in vivo and independent of the cell origin.

Cat. No.	Product Name	Target	Research Area

HY-P3692

*CART (55-76), rat*	Neuropeptide Y Receptor	Neurological Disease
CART (55-76), rat is a neuropeptide (55-76 residues of the CART peptide) and constitutes the N-terminal fragments of CART (55-102). CART (55-76), rat is a rat satiety factor with potent appetite-suppressing activity and is closely associated with leptin and neuropeptide Y. CART (55-76), rat can induce anxiety and stress-related behavior .

Cat. No.	Product Name	Target	Research Area	Image

HY-P9949

Reslizumab Sch 55700; CDP-835; JES1-39D10	Interleukin Related	Inflammation/Immunology
Reslizumab (Sch 55700) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab is effective in neutralizing the function of IL-5. Reslizumab has high binding affinity for human IL-5, with K_D values of 109 pM and 4.3 pM in the the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71497

	DNA-binding protein HU-alpha Protein, E.coli (His-SUMO) 1 Publications Verification hupA; Z5576; ECs4923DNA-binding protein HU-alpha; HU-2; NS2	E.coli	E. coli
	DNA-binding protein HU-alpha, a histone-like DNA-binding protein, wraps DNA, offering stabilization and preventing denaturation in challenging conditions. Comprising alpha and beta chains in a heterodimer, it demonstrates versatile DNA binding and protective functions. DNA-binding protein HU-alpha Protein, E.coli (His-SUMO) is the recombinant E. coli-derived DNA-binding protein HU-alpha protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

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Host:	Mouse (4)
Reactivity:	Human (4) Rat (3) Mouse (4) Monkey (1) Rabbit (1) Orangutan (1)
Application:	IHC-P (1) ICC/IF (4) WB (3) ELISA (3)
Isotype:	IgG1,IgG/Kappa (1) IgG2a (1) IgG2b (1)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (4)
Modification:	Phosphorylated (1) Unmodified (3)

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HY-P85878

	HDAC1 Antibody (YA5570) Histone deacetylase 1; HD1;	WB, ICC/IF, ELISA	Human, Mouse, Rat
	HDAC1 Antibody (YA5570) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HDAC1.

HY-P86068

	Phospho-ERK 1/2(Y222/205) Antibody (YA5760) MAPK1/MAPK3	IHC-P, ICC/IF	Human, Rat, Mouse
	Phospho-ERK 1/2(Y222/205) Antibody (YA5760) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Phospho-ERK 1/2(Y222/205).

HY-P85884

	hnRNP C1/C2 Antibody (YA5576) HNRNPC; HNRPC; Heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2	WB, ICC/IF, ELISA	Human, Mouse, Rat, Monkey, Rabbit, Orangutan
	hnRNP C1/C2 Antibody (YA5576) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to hnRNP C1/C2.

HY-P85868

	T-bet / Tbx21 Antibody (YA5560) T-box transcription factor TBX21; T-box protein 21; T-cell-specific T-box transcription factor T-bet; Transcription factor TBLYM;	WB, ICC/IF, ELISA	Human, Mouse
	T-bet / Tbx21 Antibody (YA5560) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to T-bet / Tbx21.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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