Pgam2 - phosphoglycerate mutase 2 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56012

Summary

Enables phosphoglycerate mutase activity. Acts upstream of or within Notch signaling pathway and glycolytic process. Predicted to be located in cytosol and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb mesenchyme; and sensory organ. Human ortholog(s) of this gene implicated in myoglobinuria. Orthologous to human PGAM2 (phosphoglycerate mutase 2). [provided by Alliance of Genome Resources, Apr 2022]

Pgam2 Products (1)

mRNA Protein Name
NM_018870.3 NP_061358.1 phosphoglycerate mutase 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phosphoglycerate mutase activity IDA
IDA: Inferred from direct assay
2824255 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
23446454 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Notch signaling pathway IDA
IDA: Inferred from direct assay
23117660 MGI
involved in canonical glycolysis IDA
IDA: Inferred from direct assay
23951293 MGI
acts upstream of or within glycolytic process IDA
IDA: Inferred from direct assay
15665293 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytosol IDA
IDA: Inferred from direct assay
32035422 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphoglycerate mutase 2

  • BPG-dependent PGAM 2

  • PGAM-M

  • muscle-specific phosphoglycerate mutase

  • phosphoglycerate mutase isozyme M

  • phosphoglycerate mutase muscle-specific subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10375 PGAM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21018 Pgam2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27535 Pgam2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pgam2 NCBI NCBI:5224