Msln - mesothelin Gene

Also Known as MPF

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56047

Summary

Predicted to be involved in cell-matrix adhesion. Predicted to act upstream of or within cell adhesion. Located in extracellular space. Is expressed in several structures, including body cavity or lining; genitourinary system; gut; heart; and respiratory system. Human ortholog(s) of this gene implicated in ovarian cancer; pancreas disease; pancreatic cancer; and pancreatic ductal carcinoma. Orthologous to human MSLN (Mesothelin). [provided by Alliance of Genome Resources, Apr 2022]

Msln Products (3)

mRNA Protein Name
NM_001356286.1 NP_001343215.1 mesothelin isoform 1 preproprotein
NM_001374653.1 NP_001361582.1 mesothelin isoform 2 precursor
NM_018857.2 NP_061345.1 mesothelin isoform 1 preproprotein
Protein Preferred Names Protein Names

mesothelin

  • megakaryocyte potentiating factor

  • pre-pro-megakaryocyte-potentiating factor

Recombinant Msln Proteins

Cat. No. Product Name Accession Purity
HY-P70856 Mesothelin Protein, Mouse (HEK293, His) Q61468 (D298-S600) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P78177 Mesothelin Protein, Mouse (Biotinylated, HEK293, His) Q61468 (D298-S600) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P78834 Mesothelin Protein, Mouse (Biotinylated, HEK293, His-Avi) Q61468 (D298-S600) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99006 Amatuximab Inhibitor 99.90% Phase 2
HY-P99352 Anetumab Inhibitor 98.78% Phase 2

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P11058 OVA(250-264) 98.14% Unkown
HY-185561 Misitatug blivedotin / Unkown
HY-171269 Anetumab-MMAE / Unkown
HY-P11025 TMVP1446 / Unkown
HY-P11026 DOTA-TMVP1446 / Unkown
HY-RS08719 MSLN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17193 Msln Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23644 Msln Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990833 Anti-Mesothelin Antibody (YP218) Inhibitor 95.00% Unkown
HY-P990929 Misitatug 99.00% Unkown
HY-P99663 Inezetamab Inhibitor 99.77% Unkown
HY-P991315 Anti-MSLN/Mesothelin (h7D9.v3) / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Msln NCBI NCBI:10232