Plek - pleckstrin Gene

Also Known as 2010300B13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56193

Summary

Predicted to enable phosphatidylinositol-3,4-bisphosphate binding activity; protein homodimerization activity; and protein kinase C binding activity. Involved in several processes, including exocytosis; platelet aggregation; and positive regulation of cellular component organization. Predicted to be located in cytoplasm and ruffle membrane. Predicted to be active in plasma membrane. Orthologous to human PLEK (pleckstrin). [provided by Alliance of Genome Resources, Apr 2022]

Plek Products (1)

mRNA Protein Name
NM_019549.2 NP_062422.1 pleckstrin

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in platelet aggregation IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in positive regulation of actin filament depolymerization IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in positive regulation of integrin activation IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in positive regulation of platelet activation IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in protein secretion by platelet IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in thrombin-activated receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
19190246 MGI
involved in vesicle docking involved in exocytosis IMP
IMP: Inferred from mutant phenotype
19190246 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pleckstrin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10677 PLEK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10678 PLEK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19367 Plek Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22732 Plek2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25859 Plek Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29246 Plek2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plek NCBI NCBI:5341