Uchl5 - ubiquitin carboxyl-terminal esterase L5 Gene

Also Known as Uch37; 5830413B11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56207

Summary

Predicted to enable endopeptidase inhibitor activity; Proteasome binding activity; and thiol-dependent Deubiquitinase. Involved in forebrain morphogenesis; lateral ventricle development; and midbrain development. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of Ino80 complex. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain ventricular layer; genitourinary system; nose; and orbito-sphenoid. Orthologous to human UCHL5 (ubiquitin C-terminal hydrolase L5). [provided by Alliance of Genome Resources, Apr 2022]

Uchl5 Products (2)

mRNA Protein Name
NM_001159866.1 NP_001153338.1 ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform 2
NM_019562.2 NP_062508.2 ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in forebrain morphogenesis IMP
IMP: Inferred from mutant phenotype
21048919 MGI
involved in lateral ventricle development IMP
IMP: Inferred from mutant phenotype
21048919 MGI
involved in midbrain development IMP
IMP: Inferred from mutant phenotype
21048919 MGI
involved in positive regulation of DNA repair IDA
IDA: Inferred from direct assay
23979016 MGI
involved in positive regulation of telomere maintenance in response to DNA damage IMP
IMP: Inferred from mutant phenotype
23979016 MGI
involved in regulation of DNA repair IDA
IDA: Inferred from direct assay
23979016 MGI
involved in regulation of embryonic development IMP
IMP: Inferred from mutant phenotype
23979016 MGI
involved in telomere maintenance IMP
IMP: Inferred from mutant phenotype
23979016 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase isozyme L5

  • UCH-L5

  • ubiquitin C-terminal hydrolase 37

  • ubiquitin C-terminal hydrolase UCH37

  • ubiquitin thioesterase L5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13989 b-AP15 98.05% Unkown
HY-149230 USP28-IN-4 Inhibitor 99.35% Unkown
HY-149229 USP28-IN-3 Inhibitor 98.26% Unkown
HY-D1236 Fluorescent brightener 71 Inhibitor / Unkown
HY-149228 USP28-IN-2 Inhibitor / Unkown
HY-164689 Cadmium pyrithione Inhibitor / Unkown
HY-RS15402 UCHL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-15432 (E/Z)-NSC-687852 / Unkown
HY-RS18192 Uchl5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24666 Uchl5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Uchl5 NCBI NCBI:51377