LPAR5 - lysophosphatidic acid receptor 5 Gene

Also Known as LPA5; GPR92; GPR93; KPG_010

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57121

About LPAR5

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:6,618,835-6,635,959 (from NCBI)

This gene has 3 transcripts (splice variants), 252 orthologues and 1 paralogue. Broad expression in colon (RPKM 5.6), lymph node (RPKM 4.4) and 23 other tissues.

Summary

This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008]

LPAR5 Products (2)

mRNA Protein Name
NM_020400.6 NP_065133.1 lysophosphatidic acid receptor 5
NM_001142961.1 NP_001136433.1 lysophosphatidic acid receptor 5

LPAR5 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (40 - 297)

  • 0
  • 100
  • 200
  • 300
  • 372 a.a.
Protein Preferred Names Protein Names

lysophosphatidic acid receptor 5

  • G protein-coupled receptor 92

  • G-protein coupled receptor 93

  • LPA receptor 5

  • LPA-5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-114379 AS2717638 Antagonist 99.85% Unkown
HY-15706 H2L 5765834 Antagonist 98.66% Unkown
HY-W040176 N-PTyrosine PA ammonium Modulator / Unkown
HY-148291 BrP-LPA sodium Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus LPAR5 RGD RGD:1562580
Macaca mulatta LPAR5 VGNC VGNC:74277
Canis familiaris LPAR5 VGNC VGNC:42746
Felis catus LPAR5 VGNC VGNC:82321
Mus musculus LPAR5 MGD MGI:2685918
Bos taurus LPAR5 VGNC VGNC:30959
Others LPAR5 NCBI