ADAMTSL3 - ADAMTS like 3 Gene

Homo sapiens

Also known as ADAMTSL-3

Gene ID: 57188 | Gene type: protein coding

About ADAMTSL3

Cytogenetic location: 15q25.2 Genomic coordinates (GRCh38): 15:83,654,123-84,039,842 (from NCBI)

This gene has 8 transcripts (splice variants), 193 orthologues and 25 paralogues. Broad expression in lung (RPKM 4.5), placenta (RPKM 4.0) and 24 other tissues.

Summary

Predicted to be involved in extracellular matrix organization. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

ADAMTSL3 Products(2)

mRNA	Protein	Name
NM_001301110.2	NP_001288039.1	ADAMTS-like protein 3 isoform b precursor
NM_207517.3	NP_997400.2	ADAMTS-like protein 3 isoform a precursor

ADAMTSL3 Protein Structure

TSP_1

Ig_2

I-set

TSP_1

PLAC

0
300
600
900
1200
1500
1691 a.a.

Protein Preferred Names

Protein Names

ADAMTS-like protein 3

a disintegrin-like and metalloprotease domain with thrombospondin type I motifs-like 3

Related Diseases

Diseases

Alias

Radial Nerve Lesion

Lesion Of Radial Nerve	Radial Nerve Lesions
Radial Neuropathy	Radial Nerve Mononeuritis

Geleophysic Dysplasia

Geleophysic Dwarfism

Gphysd

Isolated Ectopia Lentis

Familial Ectopia Lentis	Ectopia Lentis
Ectopia Lentis Syndrome	Lens Subluxation
Iel	Congenital Ectopia Lentis
Subluxation Of Lens	Ectopia Lentis, Isolated
Ectopia Lentis Isolated

Ehlers-Danlos Syndrome, Dermatosparaxis Type

Dermatosparaxis	EDSDERMS
Ehlers-Danlos Syndrome, Type Vii, Autosomal Recessive	Eds Viic
Eds7c	Ehlers-Danlos Syndrome Dermatosparaxis Type
Dermatosparaxis Ehlers-Danlos Syndrome	Dermatosparaxis Eds
Ehlers-Danlos Syndrome Type 7c	Deds
Human Dermatosparaxis Eds Viic	Ehlers-Danlos Syndrome 7c
Ehlers-Danlos Syndrome, Type Viic

Weill-Marchesani Syndrome

Gemss Syndrome	Spherophakia-Brachymorphia Syndrome
Marchesani-Weill Syndrome	Wms
Congenital Mesodermal Dystrophy	Mesodermal Dysmorphodystrophy, Congenital
Spherophakia Brachymorphia Syndrome	Mesodermal Dysmorphodystrophy Congenital
Wm Syndrome	Brachydactyly-Spherophakia Syndrome
Brachymorphy With Spherophakia Syndrome	Congenital Mesodermal Dysmorphodystrophy
Marchesani Syndrome	Weill-Marchesani Syndrome, Autosomal Recessive
Weill-Marchesani Syndrome, Autosomal Dominant

Peters-Plus Syndrome

Krause-Kivlin Syndrome	Peters Plus Syndrome
Peters Anomaly	Irido-Corneo-Trabecular Dysgenesis
PTRPLS	Peters Anomaly With Short-Limb Dwarfism
Peters Anomaly-Short Limb Dwarfism Syndrome	Peters Anomaly With Short Limb Dwarfism
Peters Congenital Glaucoma	Krause-Van Schooneveld-Kivlin Syndrome
Peters' Plus Syndrome	Peters'-Plus Syndrome
Anomaly Peters

Radial Neuropathy

Acromicric Dysplasia

ACMICD	Acromicric Skeletal Dysplasia
Dysplasia, Acromicric

Winchester Syndrome

WNCHRS	Winchester Disease
Winchester-Grossman Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00312	ADAMTSL3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ADAMTSL3	RGD	RGD:1305155
Macaca mulatta	ADAMTSL3	VGNC	VGNC:69400
Felis catus	ADAMTSL3	VGNC	VGNC:59601
Bos taurus	ADAMTSL3	VGNC	VGNC:58360
Canis familiaris	ADAMTSL3	VGNC	VGNC:54916
Mus musculus	ADAMTSL3	MGD	MGI:3028499

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