Extl2 - exostosin-like glycosyltransferase 2 Gene

Also Known as 3000001D04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 58193

Summary

Enables acetylgalactosaminyltransferase activity; glycosaminoglycan binding activity; and manganese ion binding activity. Involved in N-acetylglucosamine metabolic process and UDP-N-acetylgalactosamine metabolic process. Predicted to be located in cytosol; endoplasmic reticulum; and nucleoplasm. Is expressed in several structures, including central nervous system; genitourinary system; liver; lung; and spleen. Orthologous to human EXTL2 (exostosin like Glycosyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Extl2 Products (3)

mRNA Protein Name
NM_001163514.1 NP_001156986.1 exostosin-like 2 isoform a
NM_001163515.1 NP_001156987.1 exostosin-like 2 isoform b precursor
NM_021388.4 NP_067363.3 exostosin-like 2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Références Source
enables alpha-1,4-N-acetylgalactosaminyltransferase activity IMP
IMP: Inferred from mutant phenotype
12562774 MGI
enables glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity IMP
IMP: Inferred from mutant phenotype
12562774 MGI
enables glycosaminoglycan binding IMP
IMP: Inferred from mutant phenotype
12562774 MGI
enables manganese ion binding IMP
IMP: Inferred from mutant phenotype
12562774 MGI
Biological Process GO Annotation Evidence Références Source
involved in N-acetylglucosamine metabolic process IMP
IMP: Inferred from mutant phenotype
12562774 MGI
involved in UDP-N-acetylgalactosamine metabolic process IMP
IMP: Inferred from mutant phenotype
12562774 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

exostosin-like 2

  • EXT-related protein 2

  • alpha-1,4-N-acetylhexosaminyltransferase EXTL2

  • alpha-GalNAcT EXTL2

  • exostoses (multiple)-like 2

  • exostoses-like 2

  • exotoses (multiple)-like 2

  • glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase

Recombinant Extl2 Proteins

Cat. No. Nom du produit Accession Pureté
HY-P70908 EXTL2 Protein, Mouse (HEK293, His) Q9ES89 (N43-M330) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS04609 EXTL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19000 Extl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25489 Extl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Extl2 NCBI NCBI:2135