Ccnd1 - cyclin D1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 58919

Summary

Enables protein kinase binding activity. Involved in several processes, including animal organ development; response to corticosterone; and response to vitamin E. Located in cytoplasm and nucleus. Used to study prostate Cancer and status epilepticus. Biomarker of impotence; transitional cell carcinoma; and visual epilepsy. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); colorectal cancer; hematologic Cancer (multiple); invasive lobular carcinoma; and von Hippel-Lindau disease. Orthologous to human CCND1 (cyclin D1). [provided by Alliance of Genome Resources, Apr 2022]

Ccnd1 Products (1)

mRNA Protein Name
NM_171992.5 NP_741989.3 G1/S-specific cyclin-D1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein kinase binding IPI
IPI: Inferred from physical interaction
15809057 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
8651753 RGD
Biological Process GO Annotation Evidence References Source
involved in Leydig cell differentiation IMP
IMP: Inferred from mutant phenotype
17303663 RGD
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
16938172 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
15809057 RGD
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
14604889 RGD
involved in response to X-ray IEP
IEP: Inferred from expression pattern
17148264 RGD
involved in response to calcium ion IEP
IEP: Inferred from expression pattern
7980531 RGD
involved in response to corticosterone IEP
IEP: Inferred from expression pattern
12807724 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
17055086 RGD
involved in response to estrogen IEP
IEP: Inferred from expression pattern
17088081 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
17015179 RGD
involved in response to glucocorticoid IEP
IEP: Inferred from expression pattern
16707792 RGD
involved in response to iron ion IEP
IEP: Inferred from expression pattern
16890145 RGD
involved in response to magnesium ion IEP
IEP: Inferred from expression pattern
14566962 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
17137605 RGD
involved in response to steroid hormone IEP
IEP: Inferred from expression pattern
15975997 RGD
involved in response to vitamin E IEP
IEP: Inferred from expression pattern
17015179 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
12602925 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G1/S-specific cyclin-D1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0692 Schisandrol B 99.92% Unkown
HY-168664 CPD-39 Degrader 98.06% Unkown
HY-168660 CPD-10 98.59% Unkown
HY-125236 ZEN-3694 99.85% Unkown
HY-119271 CMLD010509 99.11% Unkown
HY-RS02123 CCND1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181131 Anticancer agent 300 / Unkown
HY-181769 Anticancer agent 306 / Unkown
HY-184301 EGFR/HER2-IN-20 / Unkown
HY-119271A (-)-CMLD010509 / Unkown
HY-183004 NCP26 / Unkown
HY-RS16780 Ccnd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23220 Ccnd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ccnd1 NCBI NCBI:595