CPD-39
Based on 1 Customer Validation
CPD-39 is a potent and orally active CCND1 and CDK4 heterobifunctional PROTAC degrader. CPD-39 shows anti-proliferation.
(Pink: CDK4 and CCND1 ligand (HY-50767); Blue: VHL ligand (HY-168667); Black: linker (HY-20240)).
For research use only. We do not sell to patients.
- Purity: 98.06%
- CAS No.: 3055472-38-0
- Formula: C46H57N15O4
- Molecular Weight:884.04
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Cell Cycle/DNA Damage Compound Library
HY-L004
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Anti-Cancer Compound Library
HY-L025
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Anti-Aging Compound Library
HY-L034
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Orally Active Compound Library
HY-L061
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Anti-Pancreatic Cancer Compound Library
HY-L077
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Anti-Blood Cancer Compound Library
HY-L079
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Anti-Hematopathy Compound Library
HY-L171
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Multi-Target Compound Library
HY-L176
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Protein Kinase Compound Library
HY-L196
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Cell Proliferation Compound Library
HY-L201
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High-Throughput Bioactive Compound Library
HY-L205
All PROTACs Isoforms
More
Biological Activity
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CDK4 |
CCND1 |
Chemical Information
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CAS No. 3055472-38-0
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Appearance Solid
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Molecular Weight 884.04
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Formula C46H57N15O4
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Color Colorless to light yellow
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SMILES
CC(C1=C(C2=C(N(C1=O)C3CCCC3)N=C(N=C2)NC4=CC=C(C=N4)N5CCN(CC5)CC(NC6CC7(CC(C7)NC8=NC(NC)=CC=C8C(NC9=NN=C(C=C9)N(C)C)=O)C6)=O)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (113.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1312 mL | 5.6559 mL | 11.3117 mL | 28.2793 mL |
| 5 mM | 0.2262 mL | 1.1312 mL | 2.2623 mL | 5.6559 mL | |
| 10 mM | 0.1131 mL | 0.5656 mL | 1.1312 mL | 2.8279 mL | |
| 15 mM | 0.0754 mL | 0.3771 mL | 0.7541 mL | 1.8853 mL | |
| 20 mM | 0.0566 mL | 0.2828 mL | 0.5656 mL | 1.4140 mL | |
| 25 mM | 0.0452 mL | 0.2262 mL | 0.4525 mL | 1.1312 mL | |
| 30 mM | 0.0377 mL | 0.1885 mL | 0.3771 mL | 0.9426 mL | |
| 40 mM | 0.0283 mL | 0.1414 mL | 0.2828 mL | 0.7070 mL | |
| 50 mM | 0.0226 mL | 0.1131 mL | 0.2262 mL | 0.5656 mL | |
| 60 mM | 0.0189 mL | 0.0943 mL | 0.1885 mL | 0.4713 mL | |
| 80 mM | 0.0141 mL | 0.0707 mL | 0.1414 mL | 0.3535 mL | |
| 100 mM | 0.0113 mL | 0.0566 mL | 0.1131 mL | 0.2828 mL |
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