Fetub - fetuin beta Gene

Also Known as Gugu; D17980; 2310011O17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 59083

Summary

Enables metalloendopeptidase inhibitor activity. Involved in binding activity of sperm to zona pellucida and negative regulation of endopeptidase activity. Predicted to be located in extracellular space. Predicted to be active in extracellular region. Is expressed in several structures, including genitourinary system; jaw bone; liver; muscle tissue; and olfactory epithelium. Orthologous to human FETUB (fetuin B). [provided by Alliance of Genome Resources, Apr 2022]

Fetub Products (3)

mRNA Protein Name
NM_001083904.1 NP_001077373.1 fetuin-B isoform 2
NM_001083905.1 NP_001077374.1 fetuin-B isoform 1 precursor
NM_021564.2 NP_067539.1 fetuin-B isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables metalloendopeptidase inhibitor activity IDA
IDA: Inferred from direct assay
23562279 MGI
Biological Process GO Annotation Evidence References Source
involved in binding of sperm to zona pellucida IMP
IMP: Inferred from mutant phenotype
23562279 MGI
involved in negative regulation of endopeptidase activity IDA
IDA: Inferred from direct assay
23562279 MGI
involved in single fertilization IMP
IMP: Inferred from mutant phenotype
23562279 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fetuin-B

  • IRL685

  • fetuin-like protein IRL685

Recombinant Fetub Proteins

Cat. No. Product Name Accession Purity
HY-P75195 Fetuin B Protein, Mouse (HEK293, His) Q9QXC1 (R19-P388) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04868 FETUB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19001 Fetub Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25490 Fetub Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fetub NCBI NCBI:26998