RCVRN - recoverin Gene
Also Known as RCV1
Species: Homo sapiens
About RCVRN
This gene has 2 transcripts (splice variants), 255 orthologues and 14 paralogues. Low expression observed in reference dataset.
Summary
This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. [provided by RefSeq, Jul 2008]
RCVRN Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_002903.3 | NP_002894.1 | recoverin |
RCVRN Protein Structure
EF-hand_8: EF-hand domain pair (40 - 87)
EF-hand_7: EF-hand domain pair (101 - 175)
- 0
- 100
- 200 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
recoverin |
|
Recombinant RCVRN Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P71778 | RCVRN Protein, Human (P.pastoris, His) | P35243 (G2-A200) | ≥ 90%, as determined by reducing SDS-PAGE. |
| HY-P72054 | RCVRN Protein, Human (sf9, His-Myc) | P35243 (G2-A200) | ≥ 90%, as determined by reducing SDS-PAGE. |
RCVRN Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P811127 | Recoverin Antibody | WB, IHC-P, ICC/IF | Human, Mouse, Rat |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Cancer-Associated Retinopathy |
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| Paraneoplastic Syndromes |
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| Bilateral Hypoactive Labyrinth |
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| Acquired Night Blindness |
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| Neuroretinitis |
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| Scotoma |
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| Small Cell Cancer Of The Lung |
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| Retinal Degeneration |
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| Interval Angle-Closure Glaucoma |
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| Retinitis Pigmentosa |
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| Lung Cancer |
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| Idiopathic Peripheral Autonomic Neuropathy |
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| Inner Ear Disease |
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| Macular Degeneration, Age-Related, 1 |
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| Macular Dystrophy, Dominant Cystoid |
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| Autoimmune Disease Of Eyes, Ear, Nose And Throat |
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| Autoimmune Uveitis |
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| Sympathetic Ophthalmia |
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| Birdshot Chorioretinopathy |
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| Eye Degenerative Disease |
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| Ocular Cancer |
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| Chorioretinitis |
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| Degeneration Of Macula And Posterior Pole |
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| Cone-Rod Dystrophy 2 |
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| Leber Plus Disease |
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| Stargardt Disease |
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| Congenital Stationary Night Blindness |
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| Cone Dystrophy |
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| Eye Disease |
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| Fundus Dystrophy |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | RCVRN | RGD | RGD:620258 |
| Mus musculus | RCVRN | MGD | MGI:97883 |
| Bos taurus | RCVRN | VGNC | VGNC:33838 |
| Canis familiaris | RCVRN | VGNC | VGNC:45450 |
| Felis catus | RCVRN | VGNC | VGNC:69276 |
| Others | RCVRN | NCBI |