TP53AIP1 - tumor protein p53 regulated apoptosis inducing protein 1 Gene

Also Known as P53AIP1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 63970

About TP53AIP1

Cytogenetic location: 11q24.3 Genomic coordinates (GRCh38): 11:128,934,731-128,942,871 (from NCBI)

This gene has 6 transcripts (splice variants) and 14 orthologues. Biased expression in skin (RPKM 6.8) and esophagus (RPKM 1.6).

Summary

This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent Apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

TP53AIP1 Products (4)

mRNA Protein Name
NM_001195194.1 NP_001182123.1 p53-regulated apoptosis-inducing protein 1 isoform c
NM_001195195.2 NP_001182124.1 p53-regulated apoptosis-inducing protein 1 isoform b
NM_001251964.2 NP_001238893.1 p53-regulated apoptosis-inducing protein 1 isoform d
NM_022112.3 NP_071395.2 p53-regulated apoptosis-inducing protein 1 isoform a

TP53AIP1 Protein Structure

TPIP1

TPIP1: p53-regulated apoptosis-inducing protein 1 (1 - 124)

  • 0
  • 100
  • 124 a.a.
Protein Preferred Names Protein Names

p53-regulated apoptosis-inducing protein 1

Related Diseases

Diseases Alias
Bartter Syndrome, Type 2, Antenatal

  • Bartter Disease Type 2

  • BARTS2

  • Hyperprostaglandin E Syndrome 2

  • Bartter Syndrome, Type 2

  • Bartter Syndrome Type 2

  • Hypokalemic Alkalosis With Hypercalciuria Antenatal 2

  • Hypokalemic Alkalosis With Hypercalciuria 2, Antenatal

  • Bartter Syndrome Type 2 Antenatal

  • Hypokalemic Alkalosis With Hypercalciuria 2 Antenatal

  • Bartter Syndrome Antenatal Type 2

  • Bartter Syndrome Type Ii

  • Bartter Syndrome 2, Antenatal

  • Abs2

  • Antenatal Bartter Syndrome 2

  • Bartter Syndrome 2

  • Bs2

  • Hyperprostanglandin E Syndrome 2

  • Bartter Syndrome, Antenatal , Type 2

  • Antley-Bixler Syndrome, Autosomal Dominant
Brain Cancer

  • Adult Brain Tumor

  • Malignant Neoplasm Of Brain

  • Brain Neoplasms

  • Brain Neoplasm

  • Neoplasm Of Brain

  • Primary Malignant Neoplasm Of Brain

  • Brain Tumors

  • Adult Malignant Brain Neoplasm

  • Brain Neoplasm, Adult

  • Bt - Brain Tumour

  • Malignant Brain Tumour

  • Malignant Primary Brain Neoplasm

  • Malignant Primary Brain Tumor

  • Malignant Tumor Of Adult Brain

  • Malignant Tumor Of Brain

  • Primary Brain Neoplasm

  • Primary Brain Tumor

  • Tumor Of The Brain

  • Brain Tumor, Adult

  • Brain Tumor Primary

  • Malignant Primary Brain Tumors

  • Primary Brain Tumors

  • Cancer, Brain

  • Brain Tumor, Primary
Prostate Cancer

  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-124036 DS-7423 Inhibitor 99.83% Phase 1

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14914 TP53AIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown