Entpd2 - ectonucleoside triphosphate diphosphohydrolase 2 Gene

Also Known as Cd39l1; NTPDase2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64467

Summary

Enables ATP hydrolysis activity; adenosine-diphosphatase activity; and identical protein binding activity. Involved in cellular response to cytokine stimulus; cellular response to lipopolysaccharide; and response to auditory stimulus. Located in cell body; cell projection membrane; and cell surface. Biomarker of hypertension. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human ENTPD2 (ectonucleoside triphosphate diphosphohydrolase 2). [provided by Alliance of Genome Resources, Apr 2022]

Entpd2 Products (1)

mRNA Protein Name
NM_172030.1 NP_742027.1 ectonucleoside triphosphate diphosphohydrolase 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ADP phosphatase activity IDA
IDA: Inferred from direct assay
16414200 RGD
enables ATP hydrolysis activity IDA
IDA: Inferred from direct assay
16414200 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
12694193 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to interferon-alpha IEP
IEP: Inferred from expression pattern
23990338 RGD
involved in cellular response to interleukin-6 IMP
IMP: Inferred from mutant phenotype
18202114 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
23990338 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: Inferred from expression pattern
23990338 RGD
involved in response to auditory stimulus IEP
IEP: Inferred from expression pattern
15183524 RGD
Cellular Component GO Annotation Evidence References Source
located in cell body IDA
IDA: Inferred from direct assay
12395323 RGD
located in cell projection membrane IDA
IDA: Inferred from direct assay
12395323 RGD
located in cell surface IDA
IDA: Inferred from direct assay
16414200 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ectonucleoside triphosphate diphosphohydrolase 2

  • CD39 antigen-like 1

  • NTPDase 2

  • ecto-ATP diphosphohydrolase 2

  • ecto-ATPDase 2

  • ecto-ATPase 2

  • nucleoside triphosphate diphosphohydrolase 2

  • testicular ecto-ATPase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04396 ENTPD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18863 Entpd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25355 Entpd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991917 Anti-ENTPD2 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Entpd2 NCBI NCBI:954