Adcy5 - adenylate cyclase 5 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64532

Summary

Enables calcium- and calmodulin-responsive Adenylate Cyclase activity. Involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; cAMP biosynthetic process; and response to morphine. Located in endosome; membrane raft; and plasma membrane. Colocalizes with sarcolemma. Biomarker of hypertension and type 2 diabetes mellitus. Orthologous to human ADCY5 (Adenylate Cyclase 5). [provided by Alliance of Genome Resources, Apr 2022]

Adcy5 Products (1)

mRNA Protein Name
NM_022600.2 NP_072122.2 adenylate cyclase type 5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables adenylate cyclase activity IDA
IDA: Inferred from direct assay
1409703 RGD
enables calcium- and calmodulin-responsive adenylate cyclase activity IDA
IDA: Inferred from direct assay
10894801 RGD
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
19549762 RGD
involved in cAMP biosynthetic process IDA
IDA: Inferred from direct assay
10894801 RGD
involved in heart development IEP
IEP: Inferred from expression pattern
19734365 RGD
NOT involved in negative regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
21986494 RGD
Cellular Component GO Annotation Evidence References Source
located in endosome IDA
IDA: Inferred from direct assay
17010343 RGD
located in sarcolemma IDA
IDA: Inferred from direct assay
15961389 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adenylate cyclase type 5

  • ATP pyrophosphate-lyase 5

  • adenylate cyclase type V

  • adenylyl cyclase 5

  • adenylyl cyclase type V

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00331 ADCY5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22379 Adcy5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28903 Adcy5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adcy5 NCBI NCBI:111