Apoa5 - apolipoprotein A-V Gene

Also Known as RAP3; Apoav; 1300007O05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66113

Summary

Predicted to enable several functions, including Cholesterol binding activity; enzyme activator activity; and heparin binding activity. Involved in acylglycerol homeostasis. Acts upstream of or within triglyceride metabolic process and triglyceride-rich lipoprotein particle remodeling. Predicted to be located in extracellular space. Predicted to be part of chylomicron; high-density lipoprotein particle; and very-low-density lipoprotein particle. Is expressed in lung. Human ortholog(s) of this gene implicated in cerebral infarction; coronary artery disease; familial hyperlipidemia (multiple); and type 2 diabetes mellitus. Orthologous to human APOA5 (Apolipoprotein A5). [provided by Alliance of Genome Resources, Apr 2022]

Apoa5 Products (2)

mRNA Protein Name
NM_001348095.1 NP_001335024.1 apolipoprotein A-V precursor
NM_080434.4 NP_536682.2 apolipoprotein A-V precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in acylglycerol homeostasis IMP
IMP: Inferred from mutant phenotype
11588264 MGI
acts upstream of or within triglyceride metabolic process IMP
IMP: Inferred from mutant phenotype
16166565 MGI
acts upstream of or within triglyceride-rich lipoprotein particle remodeling IMP
IMP: Inferred from mutant phenotype
16166565 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

apolipoprotein A-V

  • apolipoprotein A5

  • regeneration-associated protein 3

Recombinant Apoa5 Proteins

Cat. No. Product Name Accession Purity
HY-P77872 Apolipoprotein A-V/APOA5 Protein, Mouse (His) Q8C7G5 (R21-G368) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00832 APOA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19171 Apoa5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25660 Apoa5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Apoa5 NCBI NCBI:116519