Clec14a - C-type lectin domain family 14, member a Gene

Also Known as 1200003C23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66864

Summary

Predicted to enable extracellular matrix binding activity and extracellular matrix protein binding activity. Involved in cell migration involved in sprouting angiogenesis. Acts upstream of or within with a positive effect on vascular endothelial growth factor receptor-3 signaling pathway. Acts upstream of or within with a negative effect on vascular endothelial growth factor receptor-2 signaling pathway. Acts upstream of or within lymphangiogenesis and sprouting angiogenesis. Located in collagen-containing extracellular matrix. Is expressed in bladder; choroid plexus; diencephalon roof plate; and embryo mesenchyme. Orthologous to human CLEC14A (C-type lectin domain containing 14A). [provided by Alliance of Genome Resources, Apr 2022]

Clec14a Products (1)

mRNA Protein Name
NM_025809.5 NP_080085.3 C-type lectin domain family 14 member A precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cell migration involved in sprouting angiogenesis IMP
IMP: Inferred from mutant phenotype
25745997 MGI
acts upstream of or within lymphangiogenesis IMP
IMP: Inferred from mutant phenotype
27991863 MGI
acts upstream of or within sprouting angiogenesis IMP
IMP: Inferred from mutant phenotype
27991863 MGI
acts upstream of or within negative effect vascular endothelial growth factor receptor-2 signaling pathway IMP
IMP: Inferred from mutant phenotype
27991863 MGI
acts upstream of or within positive effect vascular endothelial growth factor receptor-3 signaling pathway IMP
IMP: Inferred from mutant phenotype
27991863 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-type lectin domain family 14 member A

Recombinant Clec14a Proteins

Cat. No. Product Name Accession Purity
HY-P76828 CLEC14A Protein, Mouse (HEK293, His) Q8VCP9 (E22-T386) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02783 CLEC14A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21996 Clec14a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28513 Clec14a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990372 Anti-CLEC14A Antibody / Unkown
HY-P990373 Anti-CLEC4C Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clec14a NCBI NCBI:161198