Mkrn2 - makorin, ring finger protein, 2 Gene

Also Known as 2610002L04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67027

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in protein ubiquitination. Is expressed in early conceptus and genitourinary system. Orthologous to human MKRN2 (makorin ring finger protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Mkrn2 Products (1)

mRNA Protein Name
NM_023290.3 NP_075779.2 E3 ubiquitin-protein ligase makorin-2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28378844 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
28378844 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of inflammatory response to antigenic stimulus IMP
IMP: Inferred from mutant phenotype
28378844 MGI
involved in negative regulation of non-canonical NF-kappaB signal transduction IDA
IDA: Inferred from direct assay
28378844 MGI
involved in ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
28378844 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
28378844 MGI
located in nucleus IDA
IDA: Inferred from direct assay
28378844 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase makorin-2

probable E3 ubiquitin-protein ligase makorin-2

  • Makorin RING zinc-finger protein 2

  • RING-type E3 ubiquitin transferase makorin-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08480 MKRN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22641 Mkrn2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29156 Mkrn2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mkrn2 NCBI NCBI:23609