Map1lc3b - microtubule-associated protein 1 light chain 3 beta Gene

Also Known as Atg8; LC3b; Map1lc3; MAP1A/MAP1B; 1010001C15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67443

Summary

Predicted to enable several functions, including ceramide binding activity; microtubule binding activity; and ubiquitin protein Ligase binding activity. Involved in Autophagy. Acts upstream of or within positive regulation of mucus secretion. Located in autolysosome; axoneme; and membrane. Is expressed in several structures, including central nervous system; heart; limb; peripheral nervous system ganglion; and sensory organ. Orthologous to several human genes including MAP1LC3B (microtubule associated protein 1 light chain 3 beta). [provided by Alliance of Genome Resources, Apr 2022]

Map1lc3b Products (2)

mRNA Protein Name
NM_001364358.1 NP_001351287.1 microtubule-associated proteins 1A/1B light chain 3B isoform 2
NM_026160.5 NP_080436.1 microtubule-associated proteins 1A/1B light chain 3B isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11890701 MGI
Biological Process GO Annotation Evidence References Source
involved in autophagy IDA
IDA: Inferred from direct assay
23629966 MGI
acts upstream of establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
24185898 MGI
acts upstream of mucus secretion IMP
IMP: Inferred from mutant phenotype
24185898 MGI
acts upstream of or within positive regulation of mucus secretion IMP
IMP: Inferred from mutant phenotype
24185898 MGI
Cellular Component GO Annotation Evidence References Source
located in autolysosome IDA
IDA: Inferred from direct assay
26284655 MGI
located in autophagosome IDA
IDA: Inferred from direct assay
22783020 MGI
located in axoneme IDA
IDA: Inferred from direct assay
24089209 MGI
located in membrane IDA
IDA: Inferred from direct assay
24185898 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

microtubule-associated proteins 1A/1B light chain 3B

  • MAP1 light chain 3-like protein 2

  • MAP1A/MAP1B light chain 3 B

  • autophagy-related protein LC3 B

  • autophagy-related ubiquitin-like modifier LC3 B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08029 MAP1LC3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-186251 C18-Pyr-Cer Inducer / Unkown
HY-RS08030 MAP1LC3B2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18108 Map1lc3b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24582 Map1lc3b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Map1lc3b NCBI NCBI:81631