Gpr183 - G protein-coupled receptor 183 Gene

Also Known as Ebi2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 679975

About Gpr183

Primary_assembly 15: 99,036,367-99,050,559 reverse strand.mRatBN7.2:CM026988.1

This gene has 2 transcripts (splice variants), 207 orthologues, 5 paralogues and is associated with 5 phenotypes. Biased expression in Spleen (RPKM 29.5), Thymus (RPKM 19.8) and 9 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity and oxysterol binding activity. Predicted to be involved in several processes, including dendritic cell homeostasis; leukocyte chemotaxis; and leukocyte differentiation. Predicted to be located in plasma membrane. Orthologous to human GPR183 (G protein-coupled receptor 183). [provided by Alliance of Genome Resources, Apr 2022]

Gpr183 Products (2)

mRNA Protein Name
NM_001109386.1 NP_001102856.1 G-protein coupled receptor 183
NM_001109386.1 NP_001102856.1 G-protein coupled receptor 183

Gpr183 Protein Structure

7tmA_EBI2

7tmA_EBI2: cd15159 (27 - 54)

7tmA_EBI2

7tmA_EBI2: cd15159 (27 - 314)

7tmA_EBI2

7tmA_EBI2: cd15159 (61 - 86)

7tmA_EBI2

7tmA_EBI2: cd15159 (99 - 129)

7tmA_EBI2

7tmA_EBI2: cd15159 (141 - 163)

7tmA_EBI2

7tmA_EBI2: cd15159 (188 - 217)

7tmA_EBI2

7tmA_EBI2: cd15159 (232 - 262)

7tmA_EBI2

7tmA_EBI2: cd15159 (282 - 307)

  • 0
  • 100
  • 200
  • 300
  • 357 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 183

  • EBV-induced G-protein coupled receptor 2

  • Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor)

  • epstein-Barr virus-induced G-protein coupled receptor 2

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-175306 GPR183 inverse agonist-1 Inhibitor / Phase 2

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-113962 7α,25-Dihydroxycholesterol Agonist 99.88% Unkown
HY-162618 PSB-KK1445 Agonist 99.80% Unkown
HY-147222 SAE-14 Antagonist 98.60% Unkown
HY-157939 GPR183 antagonist-3 Antagonist 98.79% Unkown
HY-113962S 7α,25-Dihydroxycholesterol-d6 / Unkown
HY-RS05690 GPR183 Human Pre-designed siRNA Set A / Unkown
HY-RS05691 Gpr183 Mouse Pre-designed siRNA Set A / Unkown
HY-RS05692 Gpr183 Rat Pre-designed siRNA Set A / Unkown
HY-400897 7α,25-Dihydroxycholesterol intermediate-1 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpr183 NCBI NCBI:1880