Kmt5a - lysine methyltransferase 5A Gene

Also Known as Setd8; Pr-set7; RGD1305893

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 689820

Summary

Predicted to enable histone-lysine N-methyltransferase activity; p53 binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; peptidyl-lysine monomethylation; and regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to be located in cytosol and nucleoplasm. Orthologous to human KMT5A (lysine methyltransferase 5A). [provided by Alliance of Genome Resources, Apr 2022]

Kmt5a Products (2)

mRNA Protein Name
NM_001246665.2 NP_001233594.2 N-lysine methyltransferase KMT5A isoform 1
NM_001413637.1 NP_001400566.1 N-lysine methyltransferase KMT5A isoform 2
Protein Preferred Names Protein Names

N-lysine methyltransferase KMT5A

  • N-lysine methyltransferase SETD8

  • SET domain containing (lysine methyltransferase) 8

  • SET domain-containing 8

  • histone methyltransferase Pr-set7/Set8

  • histone-lysine N-methyltransferase SETD8

  • lysine (K)-specific methyltransferase 5A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12335 UNC0379 Inhibitor 99.17% Unkown
HY-100625 BVT948 Inhibitor ≥99.0% Unkown
HY-12335A UNC0379 TFA Inhibitor 99.91% Unkown
HY-RS07406 KMT5A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18288 Kmt5a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24766 Kmt5a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kmt5a NCBI NCBI:387893