SRSF1 - Srsf1 serine and arginine rich splicing factor 1 Gene

Also Known as Sfrs1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 689890

Summary

Enables protein kinase B binding activity. Involved in several processes, including alternative mRNA splicing, via spliceosome; liver regeneration; and positive regulation of RNA splicing. Located in cytoplasm and nucleus. Biomarker of hepatocellular carcinoma. Orthologous to human SRSF1 (serine and arginine rich splicing factor 1). [provided by Alliance of Genome Resources, Apr 2022]

SRSF1 Products (1)

mRNA Protein Name
NM_001109552.2 NP_001103022.1 serine/arginine-rich splicing factor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein kinase B binding IPI
IPI: Inferred from physical interaction
15684423 RGD
Biological Process GO Annotation Evidence References Source
involved in alternative mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
23462647 RGD
involved in liver regeneration IEP
IEP: Inferred from expression pattern
23633480 RGD
involved in oligodendrocyte differentiation IEP
IEP: Inferred from expression pattern
16288477 RGD
involved in positive regulation of RNA splicing IMP
IMP: Inferred from mutant phenotype
16308321 RGD
Cellular Component GO Annotation Evidence References Source
located in nuclear envelope IDA
IDA: Inferred from direct assay
26067684 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/arginine-rich splicing factor 1

  • splicing factor, arginine/serine-rich 1

  • splicing factor, arginine/serine-rich 1B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-117661 SPHINX31 Inhibitor 99.25% Unkown
HY-P5960 PTBP1-RNA-binding inhibitor P6 TFA 98.59% Unkown
HY-170935 SRSF1-IN-1 / Unkown
HY-125201 Indazole 1 Inhibitor / Unkown
HY-183831 GPS167 / Unkown
HY-E70660 CDK13/CycK Recombinant Human Active Protein Kinase / Unkown
HY-RS13790 SRSF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17174 Srsf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23624 Srsf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SRSF1 NCBI NCBI:6426