Hint1 - histidine triad nucleotide binding protein 1 Gene

Also Known as Pkci; Prkci

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 690660

Summary

Predicted to enable adenosine 5'-monophosphoramidase activity. Predicted to be involved in several processes, including intrinsic apoptotic signaling pathway by p53 class mediator; positive regulation of calcium-mediated signaling; and protein desumoylation. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of histone deacetylase complex. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Gamstorp-Wohlfart syndrome. Orthologous to human HINT1 (histidine triad nucleotide binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Hint1 Products (1)

mRNA Protein Name
NM_001109607.1 NP_001103077.1 adenosine 5'-monophosphoramidase HINT1
Protein Preferred Names Protein Names

adenosine 5'-monophosphoramidase HINT1

  • 17 kDa inhibitor of protein kinase C

  • PKCI-1

  • adenosine 5'-monophosphoramidase

  • desumoylating isopeptidase HINT1

  • protein kinase C inhibitor 1

  • protein kinase C, iota

  • protein kinase C-interacting protein 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-113337 Ap4A Inducer / Phase 2

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-113337A Ap4A tetraammonium Inducer 99.98% Unkown
HY-138885 Tryptamine guanosine carbamate Inhibitor 99.79% Unkown
HY-173016 HINT1-IN-1 Modulator / Unkown
HY-RS06176 HINT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21594 Hint1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28112 Hint1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hint1 NCBI NCBI:3094