HINT1-IN-1
HINT1-IN-1 (Compound 8) is the inhibitor for histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. HINT1-IN-1 affects the cross-regulation between μ-opioid receptor (MOR) and NMDA receptor (NMDAR). HINT1-IN-1 enhances the analgesic effect of morphine without causing opioid tolerance and has independent analgesic effects in mouse model.
For research use only. We do not sell to patients.
- Formula: C23H24N8O5
- Molecular Weight:492.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
Chemical Information
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Molecular Weight 492.49
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Formula C23H24N8O5
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SMILES
O=C(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)N3C4=NC=C3)=C4N=C2)O1)NCCC5=CNC6=C5C=CC=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HINT1-IN-1 Related Classifications
HY-173016 Related Classifications
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