Bdh2 - 3-hydroxybutyrate dehydrogenase, type 2 Gene

Also Known as Dhrs6; 1810026B04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69772

Summary

Enables oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor. Involved in iron ion homeostasis and siderophore biosynthetic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; cranium; ear; genitourinary system; and respiratory system. Orthologous to human BDH2 (3-hydroxybutyrate dehydrogenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Bdh2 Products (2)

mRNA Protein Name
NM_001172055.1 NP_001165526.1 dehydrogenase/reductase SDR family member 6 isoform 1
NM_027208.2 NP_081484.1 dehydrogenase/reductase SDR family member 6 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor IMP
IMP: Inferred from mutant phenotype
20550936 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of positive effect intracellular sequestering of iron ion IMP
IMP: Inferred from mutant phenotype
20550936 MGI
involved in siderophore biosynthetic process IMP
IMP: Inferred from mutant phenotype
20550936 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dehydrogenase/reductase SDR family member 6

  • (R)-beta-hydroxybutyrate dehydrogenase

  • 4-oxo-L-proline reductase

  • R-beta-hydroxybutyrate dehydrogenase

  • dehydrogenase/reductase (SDR family) member 6

  • oxidoreductase UCPA

  • short chain dehydrogenase/reductase family 15C member 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01453 BDH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19878 Bdh2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26377 Bdh2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bdh2 NCBI NCBI:56898