Agk - acylglycerol kinase Gene

Also Known as Mulk; 2610037M15Rik; 6720408I04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69923

Summary

Enables acylglycerol kinase activity; ceramide kinase activity; and diacylglycerol kinase activity. Acts upstream of or within ceramide biosynthetic process and lipid phosphorylation. Located in membrane. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Sengers syndrome and cataract 38. Orthologous to human AGK (acylglycerol kinase). [provided by Alliance of Genome Resources, Apr 2022]

Agk Products (1)

mRNA Protein Name
NM_023538.2 NP_076027.1 acylglycerol kinase, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP-dependent diacylglycerol kinase activity IDA
IDA: Inferred from direct assay
15252046 MGI
enables acylglycerol kinase activity IDA
IDA: Inferred from direct assay
15252046 MGI
enables ceramide kinase activity IDA
IDA: Inferred from direct assay
15252046 MGI
enables lipid kinase activity IDA
IDA: Inferred from direct assay
15252046 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within ceramide biosynthetic process IDA
IDA: Inferred from direct assay
15252046 MGI
acts upstream of or within lipid phosphorylation IDA
IDA: Inferred from direct assay
15252046 MGI
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
15252046 MGI
located in membrane IMP
IMP: Inferred from mutant phenotype
20080761 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acylglycerol kinase, mitochondrial

  • multi-substrate lipid kinase

  • multiple substrate lipid kinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100578 AGK2 99.43% Unkown
HY-119857 AGK7 / Unkown
HY-RS00448 AGK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17725 Agk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24190 Agk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Agk NCBI NCBI:55750