Usp16 - ubiquitin specific peptidase 16 Gene

Also Known as UBPM; 1200004E02Rik; 2810483I07Rik; 6330514E22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74112

Summary

Predicted to enable several functions, including cysteine-type peptidase activity; ubiquitin binding activity; and zinc ion binding activity. Involved in monoubiquitinated histone H2A deubiquitination and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human USP16 (ubiquitin specific peptidase 16). [provided by Alliance of Genome Resources, Apr 2022]

Usp16 Products (1)

mRNA Protein Name
NM_024258.2 NP_077220.2 ubiquitin carboxyl-terminal hydrolase 16

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables histone H2A deubiquitinase activity IMP
IMP: Inferred from mutant phenotype
24034696 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24034696 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
24034696 MGI
involved in regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
24034696 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 16

  • deubiquitinating enzyme 16

  • ubiquitin specific protease 16

  • ubiquitin thioesterase 16

  • ubiquitin thiolesterase 16

  • ubiquitin-specific-processing protease 16

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15527 USP16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-172193 UBD1031 Antagonist / Unkown
HY-RS15532 USP21 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17277 Usp21 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18688 Usp16 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25174 Usp16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp16 NCBI NCBI:10600