Hsf2bp - heat shock transcription factor 2 binding protein Gene

Also Known as Meilb2; 4932437G14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74377

Summary

Involved in meiosis I and spermatogenesis. Located in chromosome. Is expressed in several structures, including genitourinary system; nervous system; sensory organ; surface ectoderm; and thymus. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 19. Orthologous to human HSF2BP (heat shock transcription factor 2 binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Hsf2bp Products (1)

mRNA Protein Name
NM_028902.1 NP_083178.1 heat shock factor 2-binding protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23707421 MGI
Biological Process GO Annotation Evidence References Source
involved in double-strand break repair involved in meiotic recombination IDA
IDA: Inferred from direct assay
30760716 MGI
involved in female meiosis I IMP
IMP: Inferred from mutant phenotype
32845237 MGI
involved in male meiosis I IDA
IDA: Inferred from direct assay
30760716 MGI
involved in spermatogenesis IDA
IDA: Inferred from direct assay
31242413 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
30760716 MGI
Cellular Component GO Annotation Evidence References Source
located in chromosome IDA
IDA: Inferred from direct assay
30760716 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heat shock factor 2-binding protein

  • meiotic localizer of BRCA2

Hsf2bp Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Hsf2bp Q9D4G2 Bnc1 Mus musculus O35914
IF
23707421
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06410 HSF2BP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21866 Hsf2bp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28383 Hsf2bp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hsf2bp NCBI NCBI:11077