Car12 - carbonic anhydrase 12 Gene

Also Known as Ca12; CA-XII; 2310047E01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76459

About Car12

Chromosome 9: 66,620,968-66,674,127 forward strand.GRCm39:CM001002.3

This gene has 6 transcripts (splice variants), 215 orthologues, 15 paralogues and is associated with 1 phenotype. Biased expression in kidney adult (RPKM 57.2), limb E14.5 (RPKM 7.3) and 5 other tissues.

Summary

This gene encodes a membrane-bound member of the alpha Carbonic Anhydrase family of Enzymes that catalyze the reversible hydration of carbon dioxide to bicarbonate. These proteins participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Car12 Products (2)

mRNA Protein Name
NM_178396.5 NP_848483.3 carbonic anhydrase 12 isoform 1 precursor
NM_001306148.1 NP_001293077.1 carbonic anhydrase 12 isoform 2 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables carbonate dehydratase activity IDA
IDA: Inferred from direct assay
14660577 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Car12 Protein Structure

alpha_CA

alpha_CA: cl00012 (38 - 289)

  • 0
  • 100
  • 200
  • 300
  • 354 a.a.
Protein Preferred Names Protein Names

carbonic anhydrase 12

  • CA XII

  • carbonate dehydratase XII

  • carbonic anhydrase XII

Recombinant Car12 Proteins

Cat. No. Product Name Accession Purity
HY-P7716 CA12/Carbonic Anhydrase 12 Protein, Mouse (HEK293, His) Q8CI85 (A25-S301) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01907 Car12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01908 Car12 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown