Gper1 - G protein-coupled estrogen receptor 1 Gene

Also Known as Gper; Ceprl; FEG-1; Gpr30; CMKRL2; GPCR-Br; 6330420K13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76854

Summary

Enables Estrogen receptor activity. Involved in several processes, including cellular chemical homeostasis; positive regulation of cell communication; and positive regulation of nitrogen compound metabolic process. Located in cytoplasm; hippocampal mossy fiber to CA3 synapse; and plasma membrane. Is expressed in embryo; metanephros; and pituitary gland. Orthologous to human GPER1 (G protein-coupled Estrogen receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Gper1 Products (1)

mRNA Protein Name
NM_029771.3 NP_084047.2 G-protein coupled estrogen receptor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables nuclear estrogen receptor activity IDA
IDA: Inferred from direct assay
23545157 MGI
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
21149639 MGI
involved in cellular response to estradiol stimulus IDA
IDA: Inferred from direct assay
21149639 MGI
involved in cellular response to glucose stimulus IDA
IDA: Inferred from direct assay
21673097 MGI
involved in modulation of chemical synaptic transmission EXP
EXP: Inferred from Experiment
29421611 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
29421611 MGI
involved in negative regulation of fat cell differentiation IDA
IDA: Inferred from direct assay
23871778 MGI
involved in negative regulation of lipid biosynthetic process IDA
IDA: Inferred from direct assay
23871778 MGI
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: Inferred from direct assay
21673097 MGI
involved in positive regulation of MAPK cascade IDA
IDA: Inferred from direct assay
23871778 MGI
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
21673097 MGI
involved in positive regulation of epidermal growth factor receptor signaling pathway IDA
IDA: Inferred from direct assay
21673097 MGI
involved in positive regulation of insulin secretion IDA
IDA: Inferred from direct assay
21673097 MGI
involved in positive regulation of neurogenesis IDA
IDA: Inferred from direct assay
23545157 MGI
involved in positive regulation of protein phosphorylation IDA
IDA: Inferred from direct assay
21673097 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
23545157 MGI
involved in regulation of cell cycle IDA
IDA: Inferred from direct assay
23871778 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
21149639 MGI
is active in hippocampal mossy fiber to CA3 synapse EXP
EXP: Inferred from Experiment
29421611 MGI
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: Inferred from direct assay
29421611 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
21149639 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G-protein coupled estrogen receptor 1

  • G-protein coupled receptor 30

  • chemoattractant receptor-like 2

  • constitutively expressed peptide-like receptor like

  • mER

  • membrane estrogen receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05636 GPER1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18518 Gper1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25000 Gper1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gper1 NCBI NCBI:2852