HKDC1 - hexokinase domain containing 1 Gene

Homo sapiens

Also known as RP92

Gene ID: 80201 | Gene type: protein coding

About HKDC1

Cytogenetic location: 10q22.1 Genomic coordinates (GRCh38): 10:69,220,332-69,267,552 (from NCBI)

This gene has 3 transcripts (splice variants), 178 orthologues, 4 paralogues and is associated with 2 phenotypes. Biased expression in duodenum (RPKM 22.5), small intestine (RPKM 21.3) and 6 other tissues.

Summary

This gene encodes a member of the Hexokinase protein family. The encoded protein is involved in glucose metabolism, and reduced expression may be associated with gestational diabetes mellitus. High expression of this gene may also be associated with poor prognosis in hepatocarcinoma. [provided by RefSeq, Sep 2016]

HKDC1 Products(1)

mRNA	Protein	Name
NM_025130.4	NP_079406.4	hexokinase HKDC1

HKDC1 Protein Structure

Hexokinase_1

Hexokinase_2

Hexokinase_1

Hexokinase_2

0
200
400
600
800
917 a.a.

Protein Preferred Names

Protein Names

hexokinase HKDC1

hexokinase domain-containing protein 1

Related Diseases

Diseases

Alias

Retinitis Pigmentosa 92

RP92	Retinitis Pigmentosa, Type 92

Orofacial Cleft 1

OFC1	Cleft Lip With Or Without Cleft Palate, Nonsyndromic, 1
Orofacial Cleft, Nonsyndromic	Ofc
Cleft Lip/Palate, Nonsyndromic	Orofacial Cleft-1
Nonsyndromic Cleft Lip With Or Without Cleft Palate 1	Nonsyndromic Cleft Lip Palate
Otofaciocervical Syndrome 1

Gestational Diabetes

Gestational Diabetes Mellitus	GDM
Diabetes Mellitus Arising In Pregnancy	Maternal Gestational Diabetes Mellitus
Diabetes Mellitus, Gestational	Diabetes Mellitus, Pregnancy Related
Diabetes, Pregnancy-Induced	Diabetes Gestational
Diabetes, Gestational	Diabetes Of Pregnancy
Gdm - [Gestational Diabetes Mellitus]	Gestational Diabetes Mellitus Nos
Gestational Diabetes Complicating Pregnancy, Childbirth, Or The Puerperium

Retinitis Pigmentosa 73

RP73	Retinitis Pigmentosa, Type 73

Diabetes Mellitus

Diabetes

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06195	HKDC1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	HKDC1	VGNC	VGNC:41701
Macaca mulatta	HKDC1	VGNC	VGNC:73432
Mus musculus	HKDC1	MGD	MGI:2384910
Rattus norvegicus	HKDC1	RGD	RGD:2321830
Bos taurus	HKDC1	VGNC	VGNC:29867

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