HKDC1 Antibody (YA2988)(PBS only)

Cat. No.: HY-P83243A: Data Sheet User Guide for Antibodies
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HKDC1 Antibody (YA2988) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HKDC1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

HKDC1 Antibody (YA2988) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HKDC1.

Host

Rabbit

Molecular Weight

Predicted band size: 103 kDa;

Observed band size: 103 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q2TB90

Gene ID

80201 [NCBI]

Immunogen

Recombinant protein of human HKDC1

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Catalyzes the phosphorylation of hexose to hexose 6-phosphate, although at very low level compared to other hexokinases (PubMed:30517626). Has low glucose phosphorylating activity compared to other hexokinases (PubMed:30517626). Involved in glucose homeostasis and hepatic lipid accumulation. Required to maintain whole-body glucose homeostasis during pregnancy; however additional evidences are required to confirm this role (By similarity)

Subcellular Localization：Cytoplasm; Mitochondrion membrane; Peripheral membrane protein; Photoreceptor inner segment

Expression：
Tissue_specificity:Widely expressed (PubMed:27459389, PubMed:29401404) . Highly expressed in the brush border, surface epithelium and the myenteric plexus of the small and large intestines; the acinar centrocytes and interlobular ducts of the pancreas; and the alveolar macrophages in the lungs (at protein level) (PubMed:29401404) . Present at moderate level in the thyroid follicular epithelium (at protein level) (PubMed:29401404)

Isoforms & Post-Translational Modification：Q2TB90 has 3 isomers: Q2TB90-1: 102545 Da (predicted); Q2TB90-2: 90575 Da (predicted); Q2TB90-3: 82682 Da (predicted).

Research Field

Signal Transduction

Synonyms

Hexokinase domain-containing protein 1

Documentation

User Guide for Antibodies (1077 KB)