Mdk - midkine Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81517

Summary

Predicted to enable glycosaminoglycan binding activity and growth factor activity. Involved in several processes, including adrenal gland development; response to glucocorticoid; and response to wounding. Located in cell projection and cytoplasm. Used to study brain infarction and coronary stenosis. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in brain ischemia. Orthologous to human MDK (midkine). [provided by Alliance of Genome Resources, Apr 2022]

Mdk Products (2)

mRNA Protein Name
NM_001413214.1 NP_001400143.1 midkine precursor
NM_030859.3 NP_110486.1 midkine precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in adrenal gland development IDA
IDA: Inferred from direct assay
11136554 RGD
involved in cell migration IDA
IDA: Inferred from direct assay
11340082 RGD
involved in response to glucocorticoid IEP
IEP: Inferred from expression pattern
12495930 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
7720861 RGD
involved in response to wounding IDA
IDA: Inferred from direct assay
10683378 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
15315716 RGD
Cellular Component GO Annotation Evidence References Source
located in cell projection IDA
IDA: Inferred from direct assay
14991843 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

midkine

  • MK

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-110171 iMDK Inhibitor 99.35% Unkown
HY-110171A iMDK quarterhydrate Inhibitor 99.37% Unkown
HY-18633 MDK83190 Activator 98.61% Unkown
HY-178164 HBS-101 99.59% Unkown
HY-RS08262 MDK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-119467 MDK0734 / Unkown
HY-RS16729 Mdk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23165 Mdk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mdk NCBI NCBI:4192