Msn - moesin Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81521

Summary

Enables actin binding activity. Predicted to be involved in several processes, including cellular response to testosterone stimulus; epithelial cell differentiation; and positive regulation of macromolecule metabolic process. Predicted to act upstream of or within positive regulation of podosome assembly. Located in several cellular components, including T-tubule; filopodium membrane; and secretory granule membrane. Human ortholog(s) of this gene implicated in immunodeficiency 50. Orthologous to human MSN (moesin). [provided by Alliance of Genome Resources, Apr 2022]

Msn Products (1)

mRNA Protein Name
NM_030863.2 NP_110490.2 moesin

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IDA
IDA: Inferred from direct assay
10945828 RGD
Cellular Component GO Annotation Evidence References Source
located in T-tubule IDA
IDA: Inferred from direct assay
19028724 RGD
located in cell surface IDA
IDA: Inferred from direct assay
10945828 RGD
located in cell tip IDA
IDA: Inferred from direct assay
17061246 RGD
located in cytoplasmic side of plasma membrane IDA
IDA: Inferred from direct assay
10945828 RGD
located in filopodium membrane IDA
IDA: Inferred from direct assay
10945828 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

moesin

  • membrane-organizing extension spike protein

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1386 D15 Inhibitor 99.02% Unkown

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12646 Rhosin hydrochloride 99.94% Unkown
HY-12646A Rhosin 98.74% Unkown
HY-120079 MSN-125 Inhibitor 99.67% Unkown
HY-118948 MSN-50 Inhibitor 98.09% Unkown
HY-140678 mPEG10000-amine 98.0% Unkown
HY-RS18452 Msn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-149410 MSN8C Inhibitor / Unkown
HY-174929 DBCO-PEG3400-Amine / Unkown
HY-174929A DBCO-PEG5000-Amine / Unkown
HY-RS08723 MSN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24933 Msn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Msn NCBI NCBI:4478