2. Gene
  3. Rps6ka1 - ribosomal protein S6 kinase A1 Gene

Rps6ka1 - ribosomal protein S6 kinase A1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as S6K-alpha 1

Gene ID: 81771 | Gene type: protein coding

About Rps6ka1

Primary_assembly 5: 146,079,021-146,118,272 reverse strand.mRatBN7.2:CM026978.1

This gene has 4 transcripts (splice variants), 218 orthologues, 7 paralogues and is associated with 2 phenotypes. Biased expression in Spleen (RPKM 156.7), Thymus (RPKM 113.2) and 9 other tissues.

Summary

Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process; protein serine/threonine/tyrosine kinase activity; and ribosomal protein S6 kinase activity. Involved in positive regulation of transcription, DNA-templated and protein phosphorylation. Located in cytoplasm and nucleus. Orthologous to human RPS6KA1 (ribosomal protein S6 kinase A1). [provided by Alliance of Genome Resources, Apr 2022]

Rps6ka1 Products(1)

mRNA Protein Name
NM_031107.2 NP_112369.2 ribosomal protein S6 kinase alpha-1

Rps6ka1 Protein Structure

STKc_RSK_N

STKc_RSK_N: cd05582 (71 - 387)

STKc_RSK1_C

STKc_RSK1_C: cd14175 (421 - 711)

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  • 741 a.a.
Protein Preferred Names Protein Names

ribosomal protein S6 kinase alpha-1

90 kDa ribosomal protein S6 kinase 1

MAP kinase-activated protein kinase 1a

MAPK-activated protein kinase 1a

MAPKAP kinase 1a

MAPKAPK-1a

MAPKAPK1A

RSK-1

S6 protein kinase (Rsk-1)

S6K-alpha-1

p90-RSK 1

p90RSK1

p90S6K

pp90RSK1

ribosomal S6 kinase 1

ribosomal protein S6 kinase polypeptide 1

ribosomal protein S6 kinase, polypeptide A1

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-123919 TL13-112 Inhibitor 98.15% Unkown
HY-122582 TL13-12 Inhibitor 98.06% Unkown
HY-148061 DB1113 99.28% Unkown
HY-136194 TL13-22 Inhibitor / Unkown
HY-136195 TL13-110 Inhibitor / Unkown
HY-RS12248 RPS6KA1 Human Pre-designed siRNA Set A / Unkown
HY-RS12249 Rps6ka1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS12250 Rps6ka1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rps6ka1 NCBI NCBI:6195