2. Gene
  3. MEX3B - mex-3 RNA binding family member B Gene

MEX3B - mex-3 RNA binding family member B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as RKHD3; MEX-3B; RNF195

Gene ID: 84206 | Gene type: protein coding

About MEX3B

Cytogenetic location: 15q25.2 Genomic coordinates (GRCh38): 15:82,041,778-82,046,018 (from NCBI)

This gene has 2 transcripts (splice variants), 189 orthologues and 3 paralogues. Biased expression in testis (RPKM 20.7), endometrium (RPKM 5.5) and 7 other tissues.

Summary

This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators. The encoded protein contains N-terminal nuclear export and nuclear localization signals and is exported from the cytoplasm to the nucleus. The protein binds to RNA via two KH domains and also colocalizes with MEX3A, Dcp1A decapping factor and Argonaute proteins within P (processing) bodies. [provided by RefSeq, Oct 2012]

MEX3B Products(1)

mRNA Protein Name
NM_032246.6 NP_115622.2 RNA-binding protein MEX3B

MEX3B Protein Structure

KH_1

KH_1: KH domain (68 - 127)

KH_1

KH_1: KH domain (162 - 221)

zf-C3HC4_3

zf-C3HC4_3: Zinc finger, C3HC4 type (RING finger) (516 - 563)

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  • 569 a.a.
Protein Preferred Names Protein Names

RNA-binding protein MEX3B

RING finger protein 195

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08373 MEX3B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MEX3B MGD MGI:1918252
Bos taurus MEX3B VGNC VGNC:54452
Felis catus MEX3B VGNC VGNC:80912
Rattus norvegicus MEX3B RGD RGD:1306790
Canis familiaris MEX3B VGNC VGNC:43184
Macaca mulatta MEX3B VGNC VGNC:74574