FYTTD1 - forty-two-three domain containing 1 Gene

Also Known as UIF

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84248

About FYTTD1

Cytogenetic location: 3q29 Genomic coordinates (GRCh38): 3:197,749,533-197,787,596 (from NCBI)

This gene has 9 transcripts (splice variants) and 209 orthologues. Ubiquitous expression in testis (RPKM 31.0), esophagus (RPKM 23.1) and 25 other tissues.

Summary

Enables mRNA binding activity. Involved in mRNA export from nucleus. Located in nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

FYTTD1 Products (2)

mRNA Protein Name
NM_001011537.3 NP_001011537.2 UAP56-interacting factor isoform 2
NM_032288.7 NP_115664.2 UAP56-interacting factor isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA binding IDA
IDA: Inferred from direct assay
19836239 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
19836239 GOA
Biological Process GO Annotation Evidence References Source
involved in mRNA export from nucleus IMP
IMP: Inferred from mutant phenotype
19836239 GOA
Cellular Component GO Annotation Evidence References Source
located in nuclear speck IDA
IDA: Inferred from direct assay
19836239 GOA
located in nucleoplasm IDA
IDA: Inferred from direct assay
19836239 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FYTTD1 Protein Structure

FYTT

FYTT: Forty-two-three protein (3 - 318)

  • 0
  • 100
  • 200
  • 300
  • 318 a.a.
Protein Preferred Names Protein Names

UAP56-interacting factor

  • forty-two-three domain-containing protein 1

FYTTD1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FYTTD1 Q96QD9 DDX39B Homo sapiens Q13838
Anti Tag CoIP
33961781
Intra
FYTTD1 Q96QD9 HNRNPC Homo sapiens P07910
Crosslink
30021884
Intra
FYTTD1 Q96QD9 HNRNPC Homo sapiens P07910
Anti Tag CoIP
33961781
Cross
FYTTD1 Q96QD9 mta_hhv8p Human herpesvirus 8 Q2HR75
Imaging
21814512
Cross
FYTTD1 Q96QD9 mta_hhv8p Human herpesvirus 8 Q2HR75
Pull Down
21814512
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Myasthenic Syndrome, Congenital, 3a, Slow-Channel

  • Congenital Myasthenic Syndrome 3a

  • CMS3A

  • Congenital Myasthenic Syndrome 3a, Slow-Channel

  • Myasthenic Syndrome, Congenital, Type 3a, Slow-Channel
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05175 FYTTD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta FYTTD1 VGNC VGNC:84178
Rattus norvegicus FYTTD1 RGD RGD:1306899
Mus musculus FYTTD1 MGD MGI:1917955
Bos taurus FYTTD1 VGNC VGNC:29164
Felis catus FYTTD1 VGNC VGNC:62401