Slc25a4 - solute carrier family 25 member 4 Gene

Also Known as Ant1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 85333

Summary

Enables enzyme binding activity. Involved in several processes, including negative regulation of cardiac muscle cell apoptotic process; negative regulation of mitochondrial membrane permeability involved in apoptotic process; and positive regulation of cell growth involved in cardiac muscle cell development. Located in membrane raft; mitochondrial inner membrane; and mitochondrial outer membrane. Biomarker of alcoholic cardiomyopathy. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); mitochondrial DNA depletion syndrome (multiple); and mitochondrial myopathy (multiple). Orthologous to human SLC25A4 (solute carrier family 25 member 4). [provided by Alliance of Genome Resources, Apr 2022]

Slc25a4 Products (1)

mRNA Protein Name
NM_053515.2 NP_445967.2 ADP/ATP translocase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
12077116 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9820802 RGD
Biological Process GO Annotation Evidence References Source
involved in heart development IEP
IEP: Inferred from expression pattern
12676547 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
9468308 RGD
involved in negative regulation of cardiac muscle cell apoptotic process IDA
IDA: Inferred from direct assay
22564366 RGD
involved in negative regulation of mitochondrial membrane permeability involved in apoptotic process IDA
IDA: Inferred from direct assay
22564366 RGD
involved in positive regulation of cell growth involved in cardiac muscle cell development IDA
IDA: Inferred from direct assay
21325829 RGD
involved in positive regulation of oxidative phosphorylation uncoupler activity IMP
IMP: Inferred from mutant phenotype
18251717 RGD
involved in response to interleukin-1 IEP
IEP: Inferred from expression pattern
15950780 RGD
Cellular Component GO Annotation Evidence References Source
located in membrane raft IDA
IDA: Inferred from direct assay
14499952 RGD
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
9820802 RGD
located in mitochondrial outer membrane IDA
IDA: Inferred from direct assay
18385140 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ADP/ATP translocase 1

  • ADP,ATP carrier protein 1

  • ANT 1

  • adenine nucleotide translocator 1

  • adenine nucleotide translocator), member 4

  • mitochondrial adenine nucleotide translocator

  • solute carrier family 25 (mitochondrial adenine nucleotide translocator) member 4

  • solute carri

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS22037 Slc25a4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13122 SLC25A4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28554 Slc25a4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc25a4 NCBI NCBI:291