Pdk4 - pyruvate dehydrogenase kinase 4 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 89813

Summary

Enables ATP binding activity and pyruvate dehydrogenase (acetyl-transferring) kinase activity. Involved in protein phosphorylation. Located in mitochondrion. Orthologous to human PDK4 (pyruvate dehydrogenase kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Pdk4 Products (1)

mRNA Protein Name
NM_053551.2 NP_446003.2 pyruvate dehydrogenase kinase, isozyme 4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
9405293 RGD
enables ATP binding IMP
IMP: Inferred from mutant phenotype
10698691 RGD
enables pyruvate dehydrogenase (acetyl-transferring) kinase activity IDA
IDA: Inferred from direct assay
9405293 RGD
enables pyruvate dehydrogenase (acetyl-transferring) kinase activity IMP
IMP: Inferred from mutant phenotype
10698691 RGD
Biological Process GO Annotation Evidence References Source
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
9405293 RGD
involved in protein phosphorylation IMP
IMP: Inferred from mutant phenotype
10698691 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pyruvate dehydrogenase kinase, isozyme 4

  • [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial

  • [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial

  • pyruvate dehydrogenase kinase, isoenzyme 4

  • pyruvate dehydrogenate kinase 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-135954A PDK4-IN-1 hydrochloride 99.72% Unkown
HY-12492 VER-246608 Inhibitor 99.10% Unkown
HY-121744 PS10 Inhibitor 98.51% Unkown
HY-135954 PDK4-IN-1 99.34% Unkown
HY-114702 M77976 Inhibitor 99.44% Unkown
HY-139185 PROTAC ERRα Degrader-3 Inhibitor 98.82% Unkown
HY-134908 DHNA Inhibitor 99.65% Unkown
HY-RS10278 PDK4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-156109 PDK-IN-2 / Unkown
HY-157538 PDK4-IN-2 Inhibitor / Unkown
HY-183318 PPARα/δ agonist 4 Agonist / Unkown
HY-116257 GSK-7227 Agonist / Unkown
HY-RS16617 Pdk4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23052 Pdk4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdk4 NCBI NCBI:5166