Ftcd - formimidoyltransferase cyclodeaminase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 89833

Summary

Enables formimidoyltetrahydrofolate cyclodeaminase activity; glutamate formimidoyltransferase activity; and microtubule binding activity. Involved in Cytoskeleton organization. Located in Golgi membrane; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. Human ortholog(s) of this gene implicated in glutamate formiminotransferase deficiency. Orthologous to human FTCD (formimidoyltransferase cyclodeaminase). [provided by Alliance of Genome Resources, Apr 2022]

Ftcd Products (1)

mRNA Protein Name
NM_053567.2 NP_446019.1 formimidoyltransferase-cyclodeaminase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables formimidoyltetrahydrofolate cyclodeaminase activity IDA
IDA: Inferred from direct assay
9677387 RGD
enables glutamate formimidoyltransferase activity IDA
IDA: Inferred from direct assay
9677387 RGD
enables microtubule binding IDA
IDA: Inferred from direct assay
9677387 RGD
Biological Process GO Annotation Evidence References Source
involved in cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
12160147 RGD
Cellular Component GO Annotation Evidence References Source
located in Golgi membrane IDA
IDA: Inferred from direct assay
9837973 RGD
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
9837973 RGD
located in endoplasmic reticulum-Golgi intermediate compartment IDA
IDA: Inferred from direct assay
9837973 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

formimidoyltransferase-cyclodeaminase

  • 58 kDa microtubule-binding protein

  • formiminotransferase cyclodeaminase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05132 FTCD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19601 Ftcd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26097 Ftcd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ftcd NCBI NCBI:10841