TSPAN18 - tetraspanin 18 Gene

Also Known as TSPAN

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 90139

About TSPAN18

Cytogenetic location: 11p11.2 Genomic coordinates (GRCh38): 11:44,726,310-44,932,423 (from NCBI)

This gene has 13 transcripts (splice variants), 254 orthologues and 32 paralogues. Broad expression in heart (RPKM 27.7), adrenal (RPKM 13.4) and 21 other tissues.

Summary

Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TSPAN18 Products (1)

mRNA Protein Name
NM_130783.5 NP_570139.3 tetraspanin-18

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in regulation of sprouting angiogenesis IMP
IMP: Inferred from mutant phenotype
32694189 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TSPAN18 Protein Structure

Tetraspannin

Tetraspannin: Tetraspanin family (8 - 246)

  • 0
  • 100
  • 200
  • 248 a.a.
Protein Preferred Names Protein Names

tetraspanin-18

  • tspan-18

TSPAN18 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
TSPAN18 Q96SJ8 FITM2 Homo sapiens Q8N6M3
Anti Tag CoIP
28514442
Intra
TSPAN18 Q96SJ8 FITM2 Homo sapiens Q8N6M3
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS15164 TSPAN18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TSPAN18 VGNC VGNC:66628
Bos taurus TSPAN18 VGNC VGNC:36433
Macaca mulatta TSPAN18 VGNC VGNC:79265
Mus musculus TSPAN18 MGD MGI:1917186
Rattus norvegicus TSPAN18 RGD RGD:1560411
Canis familiaris TSPAN18 VGNC VGNC:47917
Others TSPAN18 NCBI