Peli2 - pellino 2 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 93834

Summary

Enables protein-macromolecule adaptor activity. Predicted to be involved in protein polyubiquitination. Predicted to act upstream of or within positive regulation of MAPK cascade and positive regulation of protein phosphorylation. Located in cytosol and membrane. Is expressed in several structures, including neural tube; notochord; sensory organ; skeleton; and thymus. Orthologous to human PELI2 (pellino E3 ubiquitin protein Ligase family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Peli2 Products (1)

mRNA Protein Name
NM_033602.2 NP_291080.2 E3 ubiquitin-protein ligase pellino homolog 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12370331 MGI
enables protein-macromolecule adaptor activity IPI
IPI: Inferred from physical interaction
16831874 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
16831874 MGI
located in membrane IDA
IDA: Inferred from direct assay
16831874 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase pellino homolog 2

  • RING-type E3 ubiquitin transferase pellino homolog 2

  • protein pellino homolog 2

Peli2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Peli2 Q8BST6 Irak1 Mus musculus Q62406
Anti Tag CoIP
12370331
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10321 PELI2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22719 Peli2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29233 Peli2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Peli2 NCBI NCBI:57161