Mepe - matrix extracellular phosphoglycoprotein with ASARM motif (bone) Gene

Also Known as Of45

Species: Mus musculus

Gene Type: protein coding
Gene ID: 94111

Summary

Predicted to enable extracellular matrix protein binding activity. Acts upstream of or within negative regulation of bone mineralization. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. Is expressed in adipose tissue; aorta; brain; testis; and tibia. Orthologous to human MEPE (matrix extracellular phosphoglycoprotein). [provided by Alliance of Genome Resources, Apr 2022]

Mepe Products (1)

mRNA Protein Name
NM_053172.2 NP_444402.2 matrix extracellular phosphoglycoprotein precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of bone mineralization IMP
IMP: Inferred from mutant phenotype
12421822 MGI
acts upstream of or within negative regulation of bone mineralization IDA
IDA: Inferred from direct assay
22766095 MGI
acts upstream of or within negative regulation of bone mineralization IMP
IMP: Inferred from mutant phenotype
12421822 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

matrix extracellular phosphoglycoprotein

  • osteoblast/osteocyte factor 45

  • osteoregulin

Recombinant Mepe Proteins

Cat. No. Product Name Accession Purity
HY-P77996 MEPE/OF45 Protein, Mouse (HEK293, His) Q8K4L6 (A25-D441) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P2633A Dentonin TFA / Unkown
HY-RS08339 MEPE Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18141 Mepe Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24616 Mepe Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mepe NCBI NCBI:56955